HPLC Column, RP C8 Octyl, 5um, 2.1mm ID x 50mm Length, 100A. Cogent Brand. 1 EA.
Additional Information:
Cogent RP C8™ HPLC Columns are designed for reliable reversed-phase chromatography using a traditional octyl (C8) bonded stationary phase. Manufactured with ultra-high purity silica and fully double end capped bonding technology, these columns provide consistent retention, improved peak shape, and long service life. The RP C8™ phase is a USP L7 equivalent chemistry and is commonly used as an alternative for methods developed on comparable C8 columns. Compared to C18 phases, RP C8™ typically provides reduced retention while maintaining excellent selectivity for many hydrophobic and neutral compounds.
68508-05P-2 is packed with 5 µm RP C8™ particles featuring a 100 Å pore size in a 2.1 mm ID x 50 mm length format. This short, narrow-bore column is designed for rapid analyses while minimizing solvent consumption. The 5 µm particle size produces relatively low backpressure, making the column compatible with many HPLC and LC-MS systems. The RP C8™ stationary phase is particularly well suited for hydrophobic compounds, neutral analytes, and long-chain fatty acids where less retention than a C18 column is desired.
The 2.1 mm ID format is especially popular for LC-MS applications because reduced flow rates can improve mass spectrometer compatibility and reduce mobile phase consumption. Optimum performance typically occurs at approximately 0.2-0.3 mL/min. Standard HPLC systems used with this column must be capable of delivering reliable low flow rates with minimal pulsation, and detectors should utilize appropriately low-volume flow cells to minimize extra-column dispersion and preserve chromatographic efficiency.
Key Benefits
RP C8™ stationary phase
USP L7 equivalent chemistry
Octyl (C8) bonded phase
Fully double end capped
Ultra-high purity silica support
100 Å pore size
Fast 50 mm column length
Reduced solvent consumption
Lower retention than C18 phases
Excellent for LC-MS applications
Typical Applications
Reversed-phase HPLC
LC-MS analysis
Method development
Method scouting
Long-chain fatty acid analysis
Hydrophobic compound separations
Neutral compound analysis
Pharmaceutical analysis
Environmental testing
High-throughput screening
Specifications
Product Type: HPLC Column
Stationary Phase: RP C8™
USP Classification: L7
Chromatography Mode: Reversed Phase
Bonded Phase: Octyl (C8)
Endcapping: Fully Double End Capped
Particle Size: 5 µm
Pore Size: 100 Å
Column Dimensions: 2.1 mm ID x 50 mm
Recommended Flow Rate: 0.2-0.3 mL/min
Column Hardware: Stainless Steel
Brand: Cogent
Important Notes
Designed for fast reversed-phase HPLC and LC-MS analyses
Provides lower retention than comparable C18 columns
Suitable for hydrophobic and moderately non-polar compounds
Excellent choice for long-chain fatty acid separations
Frequently used as a scouting column during method development
50 mm length helps reduce analysis times and solvent consumption
5 µm particles provide low backpressure and broad instrument compatibility
Requires an HPLC system capable of precise and reliable low flow rate delivery
Low-volume detector flow cells are recommended to maximize performance
Manufactured using ultra-high purity silica and fully double end capped bonding technology